1. Principles of Inheritance and Variation
Genetics is the study of heredity and the variation of inherited characteristics. Gregor Mendel's experiments with pea plants laid the foundation for the principles of inheritance, including the laws of segregation and independent assortment, which describe how traits are passed from parents to offspring. Variation, arising from genetic recombination and mutation, provides the raw material for evolution. Understanding inheritance patterns is crucial for predicting traits and studying genetic disorders.
2. Molecular Basis of Inheritance
The molecular basis of inheritance involves the study of DNA (deoxyribonucleic acid) as the genetic material. DNA's double helix structure, discovered by Watson and Crick, explains how genetic information is stored and replicated. Key processes include DNA replication (copying DNA), transcription (synthesizing RNA from DNA), and translation (synthesizing proteins from RNA). Genes, segments of DNA, code for proteins that determine traits and regulate cellular functions.
3. Evolution
Evolution is the process by which populations of organisms change over successive generations, driven by mechanisms like natural selection, genetic drift, mutation, and gene flow. This leads to the diversity of life observed on Earth. Evidence for evolution comes from paleontology (fossils), comparative anatomy, embryology, biogeography, and molecular biology. Understanding evolution explains the adaptation of organisms to their environments and the emergence of new species over vast geological timescales.